Objective: To investigate the pharmacological action and mechanism of cholic acid derivatives in traditional Chinese medicine (TCM) based on the regulation of gene expression.Methods: Genome-wide gene expression profiles of Michigan Cancer Foundation-7 (MCF-7) cells treated with or without 4 cholic acid derivatives were detected by gene chip techno
The Importance of Introducing a Merit-Based Hiring System in North Macedonian Governments
In this article, the authors present several topics related to the nascent development of a merit-based hiring system in North Macedonia.This paper employs a normative approach.We advocate for a merit-based hiring system, similar to the American model.First, we explore the pressure exerted by the European Commission to adopt a merit-based system at
Missed urethral duplication associated with hypospadias, post-hypospadias repair urethral stenosis, and recurrent urinary tract infections in an adult: a case report
Abstract Background Duplication of urethra is a very rare congenital disorder.Several types of this anomaly have been reported around the world, and are also discussed in this report.However, the mechanism of this anomaly is still unclear.Case A 45-year-old Persian man with a complaint of recurrent urinary tract infection was referred to our clinic
Typology of religious spaces in the urban historical area of Lhasa, Tibet
This work focuses on the spatial compositions and characteristics of religious sites and surrounding pilgrimage space in the city of Lhasa, which is the sacred center Riding Jackets of Tibet.The modernization and urbanization of the city in recent decades have transformed the spatial and socioeconomic positions of its urban religious sites.The pres